Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

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Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma

Mesenchymal chondrosarcomas are fast-growing tumors that account for 2-10% of primary chondrosarcomas. Cytogenetic information is restricted to 12 cases that did not show a specific aberration pattern. Recently, two fusion genes were described in mesenchymal chondrosarcomas: a recurrent HEY1-NCOA2 found in tumors that had not been cytogenetically characterized and an IRF2BP2-CDX1 found in a tum...

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ژورنال

عنوان ژورنال: Genes, Chromosomes and Cancer

سال: 2011

ISSN: 1045-2257

DOI: 10.1002/gcc.20937